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Constructing Metabolic Pathways in the Malaria Parasite-Plasmodium falciparum
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  • Research
    • IoT –Enabled Smart & Connected Communities (Smart CU)
    • E-Business, e-Government
    • E-Procurement Adoption in the Nigerian Construction Industry
    • Development of Cloud based Health Information System with Medical Adherence
    • Women Development And Human Security Initiatives (WD & HSI)
    • Moderating Role of Demographic Variables and Its Impact on Life Satisfaction Among the Repatriated Migrants from Libya to Nigeria.
    • Setting up Leadership diagnostic centres in Nigeria: A Pilot Model
    • Challenges of Accountability and Development: A Multidisciplinary/Multifaceted Study of the Nigerian Society
    • Development of Saliva-based ‘Point of Care’ Diagnosis for Malaria and Detection of Resistance Markers to Arthemeter and Lumefantrine in Plasmodium falciparum from Nigeria
    • Constructing Metabolic Pathways in the Malaria Parasite-Plasmodium falciparum
    • Phytochemical, Enzymatic and Ionic Properties of Leaves and Root of selected cultivars
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    • Hand Washing and Disinfection Guidelines in Control of Spread of Infections in Hospital and Community: As Cohort Study
    • Radio-anthropogenic Assessments of Building Materials, Souls, Environment and their electro kinetic Remediation in Covenant University, Ota.
    • Assessment of Dose Reference Levels for common radio-Diagnostic procedures in South West Nigeria
    • A parametric study to enable the use mosquitos’ repelling plants in the built environment
    • Effect of Mormodica charantia and Picralima nitida on Metabolic Syndrome
    • Characterization of Anti-Cancer Compounds from Nigerian Plants
    • In vivo and In vitro Studies on the Anti-Diabetic Properties of Nauclea latifolia Sm. and Terminalia catappa L
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    • Investigation of Housing in Ogun State: Understanding the Relationship between Housing demand and provision of affordable Housing
    • Solar Powered Business Hub
    • Research on application of green organic compounds for corrosion inhibition of metallic alloys in industrial environments
    • Comparative Investigation of Maintenance of needs of Buildings in Covenant University Investigation of Housing in Ogun State
    • Summaries of ongoing Research Projects in Covenant University
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Constructing Metabolic Pathways in the Malaria Parasite-Plasmodium falciparum

Goals/Objectives of Project

  • Establishment of a computational pipeline by constructing a graph-based network structure for biochemical metabolic network.
  • Implementation of a constraint-based path finding algorithm for extracting non-liner paths.
  • Extraction of biochemically relevant, branching metabolic pathways for Plasmodium falciparum.
  • Biological validation of results to confirm expression of genes in predicted pathways and confirm genes essential to the survival of the parasite which can be used as drug targets.

List of Researchers

  • Oyelade, O. J.
  • Adebiyi, E. F.
  • Isewon Itunuoluwa
  • Solomon O. Rotimi

Contact Details of Facilitators

  • Covenant University Centre for Research, Innovation & Discovery (CUCRID)
  • Department of Computer & Information Sciences
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