Effect of Organic Phosphates on the Sulfhydryl Reactivities of Oxyhemoglobins A and S*

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The /393 sulfhydryl groups of oxyhemoglobins A and S display a difference in reactivity with 5,5’-dithiobis- 2-nitrobenzoic acid. It is concluded that this difference arises from differences in tertiary structure in the vicinity of the p”“ site. Organic phosphatesd ecrease the pg3s ulfhydryl reactivity. We have used this effect to measure the organic phosphate binding constants....

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Kehinde Okonjo

Okonjo Kehinde » Born 1942. Educated King's College, Lagos (1957-63). BSc, PhD (University of Ibadan). Retired Professor of Chemistry, University of Ibadan. Currently Professor of Chemistry, Covenant University. Current research interests: Kinetics and thermodynamics of reactions of reaction of Ellman's reagent with hemoglobin sulphydryl groups. Publications in such high impact journals as the Journal of... view full profile

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